3-Hydroxy-4-pyridinecaboxylic acid
3-Hydroxy-4-pyridinecarboxylic acid
CAS: 10128-71-9
Molecular Formula: C6H5NO3
3-Hydroxy-4-pyridinecaboxylic acid - Names and Identifiers
3-Hydroxy-4-pyridinecaboxylic acid - Physico-chemical Properties
| Molecular Formula | C6H5NO3 |
| Molar Mass | 139.11 |
| Density | 1.485±0.06 g/cm3(Predicted) |
| Melting Point | 317-319(dec.) |
| Boling Point | 519.3±35.0 °C(Predicted) |
| Flash Point | 267.9°C |
| Water Solubility | Soluble in methanol. Slightly soluble in water. |
| Vapor Presure | 1.3E-11mmHg at 25°C |
| Appearance | Solid |
| pKa | 0.51±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| MDL | MFCD00234165 |
3-Hydroxy-4-pyridinecaboxylic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
3-Hydroxy-4-pyridinecaboxylic acid - Introduction
3-Hydroxyisonicotinic acid (3-Hydroxyisonicotinic acid) is an organic compound with the chemical formula C6H12O3. The following is a description of its nature, use, preparation and safety information:
1. nature:
-Appearance: 3-Hydroxyisoniacin is a colorless to light yellow crystalline powder.
-Solubility: Soluble in water and alcohol solvents.
-Odor: Has a special smell.
2. use:
-Pharmaceutical applications: 3-hydroxyisonicotinic acid as an organic acid, can be used for the synthesis of drugs and drug intermediates, such as for the synthesis of antiviral drugs, anti-tumor drugs and hepatoprotective drugs.
-Food additives: Sometimes 3-hydroxyisoniacin can be used as a food additive to increase the acidity and taste of food.
3. Preparation method:
-3-hydroxyisonicotinic acid can be prepared by the oxidation reaction of isovaleric acid. A common method of preparation is to dissolve isovaleric acid in a sodium hydroxide solution containing oxygen and react at an appropriate temperature and pressure.
4. Safety Information:
The toxicity of-3-hydroxyisonicotinic acid is relatively low, but attention should be paid to prevent large intake or prolonged exposure.
-Avoid contact with skin, eyes and mucous membranes during use or storage.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing when operating.
-In case of inadvertent contact or swallowing, rinse immediately with plenty of water and seek medical attention promptly.
The above is an introduction to the properties, uses, preparation methods and safety information of 3-hydroxyisonicotinic acid.
1. nature:
-Appearance: 3-Hydroxyisoniacin is a colorless to light yellow crystalline powder.
-Solubility: Soluble in water and alcohol solvents.
-Odor: Has a special smell.
2. use:
-Pharmaceutical applications: 3-hydroxyisonicotinic acid as an organic acid, can be used for the synthesis of drugs and drug intermediates, such as for the synthesis of antiviral drugs, anti-tumor drugs and hepatoprotective drugs.
-Food additives: Sometimes 3-hydroxyisoniacin can be used as a food additive to increase the acidity and taste of food.
3. Preparation method:
-3-hydroxyisonicotinic acid can be prepared by the oxidation reaction of isovaleric acid. A common method of preparation is to dissolve isovaleric acid in a sodium hydroxide solution containing oxygen and react at an appropriate temperature and pressure.
4. Safety Information:
The toxicity of-3-hydroxyisonicotinic acid is relatively low, but attention should be paid to prevent large intake or prolonged exposure.
-Avoid contact with skin, eyes and mucous membranes during use or storage.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing when operating.
-In case of inadvertent contact or swallowing, rinse immediately with plenty of water and seek medical attention promptly.
The above is an introduction to the properties, uses, preparation methods and safety information of 3-hydroxyisonicotinic acid.
Last Update：2024-04-09 02:00:40
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